CDC's Overview of COVID-19 Vaccines
What You Need to Know
These vaccines are given as a shot in the muscle of the upper arm or in the thigh of a young child. COVID-19 vaccine ingredients are considered safe for most people. Nearly all of the ingredients in COVID-19 vaccines are ingredients found in many foods—fats, sugar, and salts.
None of the COVID-19 vaccines affect or interact with our DNA and the following are not included in the vaccines:
After the body produces an immune response, it discards all of the vaccine ingredients, just as it would discard any substance that cells no longer need. This process is a part of normal body functioning.
mRNA vaccines use mRNA created in a laboratory to teach our cells how to make a protein—or even just a piece of a protein—that triggers an immune response inside our bodies. The mRNA from the vaccines is broken down within a few days after vaccination and discarded from the body. Learn more about Pfizer-BioNtech COVID-19 vaccines and booster... or Moderna COVID-19 vaccines and booster...
Viral vector vaccines use a harmless, modified version of a different virus (a vector virus), and not the virus that causes COVID-19. The vector virus delivers important instructions to our cells on how to recognize and fight the virus that causes COVID-19.
Protein subunit vaccines contain pieces (proteins) of the virus that causes COVID-19. The virus pieces are the spike protein. The Novavax COVID-19 vaccine contains another ingredient called an adjuvant. It helps the immune system respond to that spike protein. After learning how to respond to the spike protein, the immune system will be able to respond quickly to the actual virus spike protein and protect you against COVID-19. Learn more about Novavax vaccines and booster...
Need Help?
Visit the CDC’s Frequently Asked Questions page for information about COVID-19 vaccinations.
You can also get answers to questions or help finding a vaccine near you in English, Spanish, and many other languages by calling:
1-800-232-0233 TTY 1-888-720-7489
Disability Information and Access Line (DIAL): 1-888-677-1199 DIAL@n4a.org
The information on this website is for informational purposes only. Consult your local medical authority for advice.
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